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FLASH GENE

Symbol

CHST11

contributors: mct - updated : 28-08-2015

HGNC name	carbohydrate (chondroitin 4) sulfotransferase 11
HGNC id	17422

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in colorectal carcinomas tumoral     --over   highly expressed in breast cancer tissues compared to normal tissues and the expression levels were significantly associated with tumor progression

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	CHST11 is independent unfavorable prognostic factor in ovarian cancer
Therapy target

ANIMAL & CELL MODELS

mouse C4st-1 as a target gene of ligands of the TGFbeta superfamily of growth factors, which could positively regulate C4st-1 expression in a number of cell types